Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease

Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease

Background: Although obstructive sleep apnea (OSA) could act as a modulator of clinical severity in sickle cell disease (SCD), few studies focused on the associations between the two diseases.Research Question: The aims of this study were: (1) to explore the associations between OSA, nocturnal oxyhe...

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Bibliographic Details
Main Authors: Emeric Stauffer, Solène Poutrel, Giovanna Cannas, Alexandra Gauthier, Romain Fort, Yves Bertrand, Céline Renoux, Philippe Joly, Camille Boisson, Arnaud Hot, Laure Peter-Derex, Vincent Pialoux, Thierry PetitJean, Philippe Connes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
sickle cell disease
nocturnal hypoxemia
hemolysis
obstructive sleep apnea
red blood cell deformability
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.743399/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.743399/full

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