Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction.

Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the bioactivity of these polymers that lead to benefi...

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Bibliographic Details
Main Authors: Aboli A Rane, Joyce S Chuang, Amul Shah, Diane P Hu, Nancy D Dalton, Yusu Gu, Kirk L Peterson, Jeffrey H Omens, Karen L Christman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3121880?pdf=render