Molecular Characterization of TP53 Gene in Human Populations Exposed to Low-Dose Ionizing Radiation

Molecular Characterization of TP53 Gene in Human Populations Exposed to Low-Dose Ionizing Radiation

Ionizing radiation, such as that emitted by uranium, may cause mutations and consequently lead to neoplasia in human cells. The TP53 gene acts to maintain genomic integrity and constitutes an important biomarker of susceptibility. The present study investigated the main alterations observed in exons...

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Main Authors: Igor Brasil-Costa, Dayse O. Alencar, Milene Raiol-Moraes, Igor A. Pessoa, Alexandre W. M. Brito, Schneyder R. Jati, Sidney E. B. Santos, Rommel M. R. Burbano, Ândrea K. C. Ribeiro-dos-Santos
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/303486

Internet

http://dx.doi.org/10.1155/2013/303486

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