Molecular Characterization of TP53 Gene in Human Populations Exposed to Low-Dose Ionizing Radiation
Ionizing radiation, such as that emitted by uranium, may cause mutations and consequently lead to neoplasia in human cells. The TP53 gene acts to maintain genomic integrity and constitutes an important biomarker of susceptibility. The present study investigated the main alterations observed in exons...
Main Authors: | Igor Brasil-Costa, Dayse O. Alencar, Milene Raiol-Moraes, Igor A. Pessoa, Alexandre W. M. Brito, Schneyder R. Jati, Sidney E. B. Santos, Rommel M. R. Burbano, Ândrea K. C. Ribeiro-dos-Santos |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2013/303486 |
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