Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway

Background: Metastasis of rhabdomyosarcoma (RMS) is the primary cause of tumour-related deaths. Previous studies have shown that overexpression of the guanine nucleotide exchange factor T (GEFT) is correlated with a poorer RMS prognosis, but the mechanism remains largely unexplored. Methods: We focu...

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Bibliographic Details
Main Authors:	Chunxia Liu, Liang Zhang, Wenwen Cui, Juan Du, Zhenzhen Li, Yuwen Pang, Qianqian Liu, Hao Shang, Lian Meng, Wanyu Li, Lingxie Song, Ping Wang, Yuwen Xie, Yuanyuan Wang, Yang Liu, Jianming Hu, Wenjie Zhang, Feng Li
Format:	Article
Language:	English
Published:	Elsevier 2019-12-01
Series:	EBioMedicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396419307352

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http://www.sciencedirect.com/science/article/pii/S2352396419307352

Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway

Internet

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