A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin.

Legionella pneumophila, the etiological agent of Legionnaires' disease, replicates intracellularly in protozoan and human hosts. Successful colonization and replication of this pathogen in host cells requires the Dot/Icm type IVB secretion system, which translocates approximately 300 effector p...

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Bibliographic Details
Main Authors: Yao Liu, Wenhan Zhu, Yunhao Tan, Ernesto S Nakayasu, Christopher J Staiger, Zhao-Qing Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5298343?pdf=render