c-Abl inhibitors enable insights into the pathophysiology and neuroprotection in Parkinson’s disease

c-Abl inhibitors enable insights into the pathophysiology and neuroprotection in Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder causing movement disabilities and several non-motor symptoms in afflicted patients. Recent studies in animal models of PD and analyses of brain specimen from PD patients revealed an increase in the level and activity of the non-rec...

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Bibliographic Details
Main Authors: Dan Lindholm, Dan Duc Pham, Annunziata Cascone, Ove Eriksson, Krister Wennerberg, Mart Saarma
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Leukemia
Parkinson’s disease
parkin
α-Synuclein
c-Abl
nilotinib
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00254/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00254/full

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