Attenuated Disease in SIV-Infected Macaques Treated with a Monoclonal Antibody against FasL

Acute SIVmac infection in macaques is accompanied by high levels of plasma viremia that decline with the appearance of viral immunity and is a model for acute HIV disease in man. Despite specific immune responses, the virus establishes a chronic, persistent infection. The destruction of CD4+ and C...

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Bibliographic Details
Main Authors: Maria S. Salvato, C. Cameron Yin, Hideo Yagita, Toshihiro Maeda, Ko Okumura, Ilia Tikhonov, C. David Pauza
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2007/93462