Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.

Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.

It is of great interest to understand how invading pathogens are sensed within the brain, a tissue with unique challenges to mounting an immune response. The eukaryotic parasite Toxoplasma gondii colonizes the brain of its hosts, and initiates robust immune cell recruitment, but little is known abou...

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Bibliographic Details
Main Authors: Katherine M Still, Samantha J Batista, Carleigh A O'Brien, Oyebola O Oyesola, Simon P Früh, Lauren M Webb, Igor Smirnov, Michael A Kovacs, Maureen N Cowan, Nikolas W Hayes, Jeremy A Thompson, Elia D Tait Wojno, Tajie H Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009027

Internet

https://doi.org/10.1371/journal.ppat.1009027

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