Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra

Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra

Cerebral dopamine neurotrophic factor (CDNF) has shown therapeutic potential in rodent and non-human primate models of Parkinson’s disease by protecting the dopamine neurons from degeneration and even restoring their phenotype and function. Previously, neurorestorative efficacy of CDNF in the 6-hydr...

Full description

Bibliographic Details
Main Authors: Katrina Albert, Juho-Matti Renko, Kert Mätlik, Mikko Airavaara, Merja H. Voutilainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
cerebral dopamine neurotrophic factor
substantia nigra
Parkinson’s disease
striatum
diffusion
transport
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00590/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00590/full

Similar Items