Modular Organization of Engulfment Receptors and Proximal Signaling Networks: Avenues to Reprogram Phagocytosis

Modular Organization of Engulfment Receptors and Proximal Signaling Networks: Avenues to Reprogram Phagocytosis

Transmembrane protein engulfment receptors expressed on the surface of phagocytes engage ligands on apoptotic cells and debris to initiate a sequence of events culminating in material internalization and immunologically beneficial outcomes. Engulfment receptors are modular, comprised of functionally...

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Bibliographic Details
Main Authors: Emily A. Britt, Vanessa Gitau, Amara Saha, Adam P. Williamson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
phagocytosis
engulfment
immune receptor
signal transduction
macrophage reprogramming
chimeric antigen receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661974/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.661974/full

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