Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis

Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis

Abstract Background Previous basic research and clinical studies examined the effects of mesenchymal stem cells (MSCs) on regeneration and maintenance of articular cartilage. However, our pilot study suggested that MSCs are more effective at suppressing inflammation and pain rather than promoting ca...

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Bibliographic Details
Main Authors: Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, Ai Takahashi, Kazuya Honjoh, Hideaki Nakajima, Hisashi Oki, Yasuo Kokubo, Akihiko Matsumine
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Musculoskeletal Disorders
Subjects:
Processed lipoaspirate (PLA) cells
Mesenchymal stem cells (MSCs)
Adipose derived-mesenchymal stem cells (AD-MSCs)
Intra-articular injection
Osteoarthritis (OA)
Monoiodoacetate (MIA)
Online Access:http://link.springer.com/article/10.1186/s12891-019-2710-1

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http://link.springer.com/article/10.1186/s12891-019-2710-1

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