Cryo-EM structure of alpha-synuclein fibrils

Cryo-EM structure of alpha-synuclein fibrils

Parkinson’s disease is a progressive neuropathological disorder that belongs to the class of synucleinopathies, in which the protein alpha-synuclein is found at abnormally high concentrations in affected neurons. Its hallmark are intracellular inclusions called Lewy bodies and Lewy neurites. We here...

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Bibliographic Details
Main Authors: Ricardo Guerrero-Ferreira, Nicholas MI Taylor, Daniel Mona, Philippe Ringler, Matthias E Lauer, Roland Riek, Markus Britschgi, Henning Stahlberg
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
Parkinson's disease
alpha-synuclein
fibril
cryo-electron microscopy
structural biology
neurodegeneration
Online Access:https://elifesciences.org/articles/36402

Internet

https://elifesciences.org/articles/36402

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