Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.

We herein demonstrate the immune-regulatory effect of embryonic stem cell-derived dendritic cells (ES-DCs) using two models of autoimmune disease, namely non-obese diabetic (NOD) mice and experimental autoimmune encephalomyelitis (EAE). Treatment of pre-diabetic NOD mice with ES-DCs exerted almost c...

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Bibliographic Details
Main Authors: Tokunori Ikeda, Shinya Hirata, Koutaro Takamatsu, Miwa Haruta, Hirotake Tsukamoto, Takaaki Ito, Makoto Uchino, Yukio Ando, Seiho Nagafuchi, Yasuharu Nishimura, Satoru Senju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4270741?pdf=render