The Inhibition of NLRP3 Inflammasome and IL-6 Production by <i>Hibiscus noldeae Baker f. </i>Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials

The Inhibition of NLRP3 Inflammasome and IL-6 Production by <i>Hibiscus noldeae Baker f. </i>Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials

The activation of NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome and/or its components is associated with the physio-pathogenesis of many respiratory diseases including asthma, COPD (chronic obstructive pulmonary disease), SARS Cov-2 (severe acute respiratory syndrome coronav...

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Bibliographic Details
Main Authors: Jean Claude Didelot Tomani, Vedaste Kagisha, Alembert Tiabou Tchinda, Olivia Jansen, Allison Ledoux, Luc Vanhamme, Michel Frederich, Raymond Muganga, Jacob Souopgui
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
asthma
<i>Hibiscus noldeae</i>
bio-guided fractionation
Inflammasome
IL-1β
IL-6
Online Access:https://www.mdpi.com/1420-3049/25/20/4693

Internet

https://www.mdpi.com/1420-3049/25/20/4693

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