SUMOFLUX: A Generalized Method for Targeted 13C Metabolic Flux Ratio Analysis.

Metabolic fluxes are a cornerstone of cellular physiology that emerge from a complex interplay of enzymes, carriers, and nutrients. The experimental assessment of in vivo intracellular fluxes using stable isotopic tracers is essential if we are to understand metabolic function and regulation. Flux e...

Full description

Bibliographic Details
Main Authors: Maria Kogadeeva, Nicola Zamboni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5023139?pdf=render