Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis Pigmentosa

Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis Pigmentosa

Hereditary retinal degenerations like retinitis pigmentosa (RP) are among the leading causes of blindness in younger patients. To enable in vivo investigation of cellular and molecular mechanisms responsible for photoreceptor cell death and to allow testing of therapeutic strategies that could preve...

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Bibliographic Details
Main Authors: Christina B. Bielmeier, Saskia Roth, Sabrina I. Schmitt, Stefaniya K. Boneva, Anja Schlecht, Mario Vallon, Ernst R. Tamm, Süleyman Ergün, Andreas Neueder, Barbara M. Braunger
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
retinitis pigmentosa
VPP mouse model
in-situ hybridization
neurodegeneration
neuroinflammation
extracellular matrix disorganisation
Online Access:https://www.mdpi.com/1422-0067/22/12/6307

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https://www.mdpi.com/1422-0067/22/12/6307

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