Alternative RNA Structure-Coupled Gene Regulations in Tumorigenesis

Alternative RNA Structure-Coupled Gene Regulations in Tumorigenesis

Alternative RNA structures (ARSs), or alternative transcript isoforms, are critical for regulating cellular phenotypes in humans. In addition to generating functionally diverse protein isoforms from a single gene, ARS can alter the sequence contents of 5'/3' untranslated regions (UTRs) an...

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Bibliographic Details
Main Author: Feng-Chi Chen
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
gene regulation
alternative splicing
alternative promoter usage
alternative cleavage and polyadenylation
untranslated region
nonsense-mediated decay
upstream open reading frame
internal ribosome entry site
microRNA
tumorigenesis
Online Access:http://www.mdpi.com/1422-0067/16/1/452

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http://www.mdpi.com/1422-0067/16/1/452

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