Artemisinin-Daumone Hybrid Inhibits Cancer Cell-Mediated Osteolysis by Targeting Cancer Cells and Osteoclasts

Artemisinin-Daumone Hybrid Inhibits Cancer Cell-Mediated Osteolysis by Targeting Cancer Cells and Osteoclasts

Background/Aims: Bone metastasis of cancer cells decreases patient survival and quality of life. Hybridization via the covalent coupling of two bioactive natural products is a useful strategy for developing more potent anticancer agents by enhancing their bioavailability and avoiding drug resistance...

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Bibliographic Details
Main Authors: Gwang Taek Ma, Sun Kyoung Lee, Kwang-Kyun Park, Junhee Park, Seung Hwa Son, Mankil Jung, Won-Yoon  Chung
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Artemisinin
Daumone
Hybrid molecules
Bone metastasis
Cancer-associated osteolysis
Online Access:https://www.karger.com/Article/FullText/493449

Internet

https://www.karger.com/Article/FullText/493449

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