Docetaxel Enhances the Expression of STING Protein in PC3 Cells, and cGAMP Attenuates this Effect

Background: The stimulator of interferon genes (STING) agonist (cGAMP) kills the cancer cells through the activation of the innate immune system. PC3 cells are high in BTK and low in STING. In this study, the effect of adding STING agonist, cGAMP, to docetaxel investigated. Materials and Methods:...

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Bibliographic Details
Main Authors: Shaghayegh Salimi, Mitra Rezaei, Zahra Mousavi, Roya Atabakhshian, Ramin PourIran, Seyed Ali Ziai
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2020-11-01
Series:Novelty in Biomedicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/nbm/article/view/30845