Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study.

The formation and maintenance of granulomas is central to the host response to Mycobacterium tuberculosis (Mtb) infection. It is widely accepted that the lungs of patients with tuberculosis (TB) usually contain multiple infection foci, and that the granulomas evolve and differentiate independently,...

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Main Authors: Selvakumar Subbian, Liana Tsenova, Mi-Jeong Kim, Helen C Wainwright, Annalie Visser, Nirmalya Bandyopadhyay, Joel S Bader, Petros C Karakousis, Gabriele B Murrmann, Linda-Gail Bekker, David G Russell, Gilla Kaplan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4489805?pdf=render