Genetics and Sex in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS): Is There a Link?

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known cure. Approximately 90% of ALS cases are sporadic, although multiple genetic risk factors have been recently revealed also in sporadic ALS (SALS). The pathological expansion of a hexanucleotide repeat in <i>...

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Bibliographic Details
Main Authors: Francesca Trojsi, Giulia D’Alvano, Simona Bonavita, Gioacchino Tedeschi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
sex
Online Access:https://www.mdpi.com/1422-0067/21/10/3647