Efficacy of AST-120 for Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials

Efficacy of AST-120 for Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials

AST-120, an oral spherical activated carbon, may delay the need for kidney dialysis and improve uremia symptoms because it can adsorb acidic and basic organic compounds, especially small-molecule uremic toxins. However, previous studies produced no conclusive evidence regarding the benefits of AST-1...

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Bibliographic Details
Main Authors: Pei-Yu Su, Ya-Han Lee, Li-Na Kuo, Yen-Cheng Chen, Chiehfeng Chen, Yi-No Kang, Elizabeth H. Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
chronic renal failure
adsorbent
kremezin
uremic toxin
sorbent
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.676345/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.676345/full

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