SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release

SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release

Polyomaviruses are a family of small, non-enveloped DNA viruses that can cause severe disease in immunosuppressed individuals. Studies with SV40, a well-studied model polyomavirus, have revealed the role of host proteins in polyomavirus entry and trafficking to the nucleus, in viral transcription an...

Full description

Bibliographic Details
Main Authors: Nasim Motamedi, Xaver Sewald, Yong Luo, Walther Mothes, Daniel DiMaio
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
Simian virus 40
vacuoles
GM1
lytic infection
progressive multifocal leukoencephalopathy
PML
Online Access:https://www.mdpi.com/1999-4915/12/10/1128

Internet

https://www.mdpi.com/1999-4915/12/10/1128

Similar Items