Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation

Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation

Background: Tumour-derived extracellular vesicles (EVs) play a role in tumour progression; however, the spectrum of molecular mechanisms regulating EV secretion and cargo selection remain to be fully elucidated. We have reported that cavin-1 expression in prostate cancer PC3 cells reduced the abunda...

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Bibliographic Details
Main Authors: Kerry L. Inder, Jayde E. Ruelcke, Lara Petelin, Hyeongsun Moon, Eunju Choi, James Rae, Antje Blumenthal, Dietmar Hutmacher, Nicholas A. Saunders, Jennifer L. Stow, Robert G. Parton, Michelle M. Hill
Format: Article
Language:English
Published: Taylor & Francis Group 2014-06-01
Series:Journal of Extracellular Vesicles
Subjects:
polymerase I and transcript release factor
osteoclast
exosomes
metastasis
caveolin
caveolae
prostasome
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/download/23784/34309

Internet

http://www.journalofextracellularvesicles.net/index.php/jev/article/download/23784/34309

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