DETERMINATION OF CAPECITABINE AND ITS ACTIVE METABOLITE 5-FLUOROURACIL IN BLOOD PLASMA BY HPLC-MS/MS
A method for quantification of capecitabine and 5-fluorouracil in human plasma was developed. The sample preparation was carried out by protein precipitation with methanol. The quantitative determination was performed by HPLC with a triple quadrupole mass-detector. The method was validated in terms...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/100 |