Dual functions for the ssDNA-binding protein RPA in meiotic recombination.

Meiotic recombination permits exchange of genetic material between homologous chromosomes. The replication protein A (RPA) complex, the predominant ssDNA-binding complex, is required for nearly all aspects of DNA metabolism, but its role in mammalian meiotic recombination remains unknown due to the...

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Bibliographic Details
Main Authors: Baolu Shi, Jiangyang Xue, Hao Yin, Rui Guo, Mengcheng Luo, Lan Ye, Qinghua Shi, Xiaoyan Huang, Mingxi Liu, Jiahao Sha, P Jeremy Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007952