Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers
Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major regulatory step, an irreversible reaction of oxidative decarboxylation of pyruvate to a...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Diabetes Association
2015-06-01
|
| Series: | Diabetes & Metabolism Journal |
| Subjects: | |
| Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-188.pdf |