Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation

Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation

ObjectivesTo determine the effects of genetic polymorphisms of ABCB1 (MDR1), CYP2A6, CYP2B6 on smoking status, and clinical outcomes of smoking cessation therapies in a Turkish population.Methods130 smokers and 130 non-smokers were recruited. Individuals who never smoked were described as non-smoker...

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Bibliographic Details
Main Authors: Ahmet Muderrisoglu, Elif Babaoglu, Elif Tugce Korkmaz, Mert C. Ongun, Erdem Karabulut, Alper B. Iskit, Salih Emri, Melih O. Babaoglu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
nicotine
genetic polymorphism
addiction
P-glycoprotein
cytochrome P450 enzymes
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.571997/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.571997/full

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