TC10 is regulated by caveolin in 3T3-L1 adipocytes.

TC10 is a small GTPase found in lipid raft microdomains of adipocytes. The protein undergoes activation in response to insulin, and plays a key role in the regulation of glucose uptake by the hormone.TC10 requires high concentrations of magnesium in order to stabilize guanine nucleotide binding. Kin...

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Bibliographic Details
Main Authors: Dave Bridges, Louise Chang, Irfan J Lodhi, Natalie A Clark, Alan R Saltiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3416860?pdf=render