CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis

CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis

Up to 40% of advance lung, melanoma and breast cancer patients suffer from brain metastases (BM) with increasing incidence. Here, we assessed whether circulating tumor cells (CTCs) in peripheral blood can serve as a disease surrogate, focusing on CD44 and CD74 expression as prognostic markers for BM...

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Bibliographic Details
Main Authors: Desiree Loreth, Moritz Schuette, Jenny Zinke, Malte Mohme, Andras Piffko, Svenja Schneegans, Julia Stadler, Melanie Janning, Sonja Loges, Simon A. Joosse, Katrin Lamszus, Manfred Westphal, Volkmar Müller, Markus Glatzel, Jakob Matschke, Christoffer Gebhardt, Stefan W. Schneider, Iwona Belczacka, Beate Volkmer, Rüdiger Greinert, Marie-Laure Yaspo, Patrick N. Harter, Klaus Pantel, Harriet Wikman
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
brain metastasis
circulating tumor cells
breast cancer
NSCLC
melanoma
Online Access:https://www.mdpi.com/1422-0067/22/13/6993

Internet

https://www.mdpi.com/1422-0067/22/13/6993

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