From Genome to Drugs: New Approaches in Antimicrobial Discovery

From Genome to Drugs: New Approaches in Antimicrobial Discovery

Decades of successful use of antibiotics is currently challenged by the emergence of increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario where private investment in the development of new antimicrobials is declining, efforts to combat drug-resistant infecti...

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Bibliographic Details
Main Authors: Federico Serral, Florencia A. Castello, Ezequiel J. Sosa, Agustín M. Pardo, Miranda Clara Palumbo, Carlos Modenutti, María Mercedes Palomino, Alberto Lazarowski, Jerónimo Auzmendi, Pablo Ivan P. Ramos, Marisa F. Nicolás, Adrián G. Turjanski, Marcelo A. Martí, Darío Fernández Do Porto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
drug discovery
drug target
metabolic reconstruction
structural modeling
target prioritization
virtual screening
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.647060/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.647060/full

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