Display of malaria transmission-blocking antigens on chimeric duck hepatitis B virus-derived virus-like particles produced in Hansenula polymorpha.

BACKGROUND:Malaria caused by Plasmodium falciparum is one of the major threats to human health globally. Despite huge efforts in malaria control and eradication, highly effective vaccines are urgently needed, including vaccines that can block malaria transmission. Chimeric virus-like particles (VLP)...

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Bibliographic Details
Main Authors: David Wetzel, Jo-Anne Chan, Manfred Suckow, Andreas Barbian, Michael Weniger, Volker Jenzelewski, Linda Reiling, Jack S Richards, David A Anderson, Betty Kouskousis, Catherine Palmer, Eric Hanssen, Gerhard Schembecker, Juliane Merz, James G Beeson, Michael Piontek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221394