Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo.

Targeting dendritic cell-specific endocytic receptors using monoclonal antibodies fused to desired antigens is an approach widely used in vaccine development to enhance the poor immunogenicity of protein-based vaccines and to induce immune responses. Here, we engineered an anti-human DCIR recombinan...

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Bibliographic Details
Main Authors: Anne-Laure Flamar, Vanessa Contreras, Sandra Zurawski, Monica Montes, Nathatlie Dereuddre-Bosquet, Frédéric Martinon, Jacques Banchereau, Roger Le Grand, Gerard Zurawski, Yves Levy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4583231?pdf=render