Dysregulation of miR-375/AEG-1 Axis by Human Papillomavirus 16/18-E6/E7 Promotes Cellular Proliferation, Migration, and Invasion in Cervical Cancer

Dysregulation of miR-375/AEG-1 Axis by Human Papillomavirus 16/18-E6/E7 Promotes Cellular Proliferation, Migration, and Invasion in Cervical Cancer

Cervical Cancer (CC) is a highly aggressive tumor and is one of the leading causes of cancer-related deaths in women. miR-375 was shown to be significantly down-regulated in cervical cancer cells. However, the precise biological functions of miR-375 and the molecular mechanisms underlying its action...

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Bibliographic Details
Main Authors: Sridharan Jayamohan, Maheshkumar Kannan, Rajesh Kannan Moorthy, Nirmal Rajasekaran, Hun Soon Jung, Young Kee Shin, Antony Joseph Velanganni Arockiam
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
human papillomavirus
miR-375
astrocyte elevated gene-1
cervical cancer
cell proliferation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00847/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00847/full

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