Neuronal migration disorders

Lissencephaly–pachygyria-severe band heterotopia are diffuse neuronal migration disorders (NMDs) causing severe, global neurological impairment. Abnormalities of the LIS1, DCX, ARX, TUBA1A and RELN genes have been associated with these malformations. NMDs only affecting subsets of neurons, such as m...

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Bibliographic Details
Main Authors: Renzo Guerrini, Elena Parrini
Format: Article
Language:English
Published: Elsevier 2010-05-01
Series:Neurobiology of Disease
Subjects:
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000369