Clonal Confinement of a Highly Mobile Resistance Element Driven by Combination Therapy in Rhodococcus equi

Clonal Confinement of a Highly Mobile Resistance Element Driven by Combination Therapy in Rhodococcus equi

MDR clades arise upon acquisition of resistance traits, but the determinants of their clonal expansion remain largely undefined. Taking advantage of the unique features of Rhodococcus equi infection control in equine farms, involving the same dual antibiotic treatment since the 1980s (a macrolide an...

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Bibliographic Details
Main Authors: Sonsiray Álvarez-Narváez, Steeve Giguère, Elisa Anastasi, Jack Hearn, Mariela Scortti, José A. Vázquez-Boland
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mBio
Subjects:
isre46
mdr clonality
rhodococcus equi
rhodococcus equi mdr clone
rhodococcus hoagii
rhodococcus pneumonia
tnrerm46
erm(46)
macrolide resistance
multidrug resistance
prerm46
rifampin resistance
Online Access:https://doi.org/10.1128/mBio.02260-19

Internet

https://doi.org/10.1128/mBio.02260-19

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