Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study

Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study

It is unknown if the somatic mutations in chronic myeloproliferative neoplasms (MPNs), JAK2V617F and Calreticulin, are associated with oxidative stress, or impaired mitochondrial defense against reactive oxygen species. In the Danish General Suburban Population Study (GESUS), including 116 JAK2V617F...

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Bibliographic Details
Main Authors: Anders L. Sørensen, Hans C. Hasselbalch, Mads Emil Bjørn, Claus H. Nielsen, Sabrina Cordua, Vibe Skov, Lasse Kjær, Henrik E. Poulsen, Christina Ellervik
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Oxidized nucleosides
8-oxodG
8-oxoGuo
Oxidative stress
JAK2V617F
CALR
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000434

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http://www.sciencedirect.com/science/article/pii/S2213231721000434

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