Concentration Sensing by the Moving Nucleus in Cell Fate Determination: A Computational Analysis.

During development of the vertebrate neuroepithelium, the nucleus in neural progenitor cells (NPCs) moves from the apex toward the base and returns to the apex (called interkinetic nuclear migration) at which point the cell divides. The fate of the resulting daughter cells is thought to depend on th...

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Bibliographic Details
Main Authors: Varun Aggarwal, Richard B Dickinson, Tanmay P Lele
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752345?pdf=render