The roles of kinetochore of micronucleus in mitosis of HeLa cells: a live cell imaging study

The roles of kinetochore of micronucleus in mitosis of HeLa cells: a live cell imaging study

Abstract Background Micronuclei (MNi) are extensively used to evaluate genotoxic effects and chromosome instability. However, the roles of kinetochore of MN in mitosis have not been completely addressed. Methods The HeLa CENP B-GFP H2B-mCherry cells are applied to address these questions via the lon...

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Bibliographic Details
Main Authors: Erkang Jiang, Lianping Wei, Fang Tao, Mei Yu, Shu Wang, Xiuhong Zhou, Daxiang Li, Zhongwen Xie
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Cell International
Subjects:
Micronucleus
Kinetochore
Lagging chromosome
Chromosome fragment
Mitosis
Live cell imaging
Online Access:http://link.springer.com/article/10.1186/s12935-019-0917-8

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http://link.springer.com/article/10.1186/s12935-019-0917-8

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