A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro

Most tumors consume large amounts of glucose. Concepts to explain the mechanisms that mediate the achievement of this metabolic need have proposed a switch of the tumor mass to aerobic glycolysis. Depending on whether primarily tumor or stroma cells undergo such a commutation, the terms ‘Warburg eff...

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Bibliographic Details
Main Authors: Florian Keller, Roman Bruch, Richard Schneider, Julia Meier-Hubberten, Mathias Hafner, Rüdiger Rudolf
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
LC3
Online Access:https://www.mdpi.com/2073-4409/9/8/1900