Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival.

Mesothelin is a cell surface associated antigen expressed on mesothelial cells and in some malignant neoplasms. Mesothelin-targeted therapies are in phase I/II clinical trials. The clinicopathologic and prognostic significance of mesothelin expression in triple negative breast carcinomas (TNBC) has...

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Bibliographic Details
Main Authors: Gary Tozbikian, Edi Brogi, Kyuichi Kadota, Jeffrey Catalano, Muzaffar Akram, Sujata Patil, Alice Y Ho, Jorge S Reis-Filho, Britta Weigelt, Larry Norton, Prasad S Adusumilli, Hannah Yong Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4266616?pdf=render