Sa12b Peptide from Solitary Wasp Inhibits ASIC Currents in Rat Dorsal Root Ganglion Neurons

In this work, we evaluate the effect of two peptides Sa12b (EDVDHVFLRF) and Sh5b (DVDHVFLRF-NH<sub>2</sub>) on Acid-Sensing Ion Channels (ASIC). These peptides were purified from the venom of solitary wasps <i>Sphex argentatus argentatus</i> and <i>Isodontia harmandi<...

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Bibliographic Details
Main Authors: Carmen Hernández, Katsuhiro Konno, Emilio Salceda, Rosario Vega, André Junqueira Zaharenko, Enrique Soto
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/10/585