Chromosome (re)positioning in spermatozoa of fathers and sons – carriers of reciprocal chromosome translocation (RCT)

Chromosome (re)positioning in spermatozoa of fathers and sons – carriers of reciprocal chromosome translocation (RCT)

Abstract Background Non-random chromosome positioning has been observed in the nuclei of several different tissue types, including human spermatozoa. The nuclear arrangement of chromosomes can be altered in men with decreased semen parameters or increased DNA fragmentation and in males with chromoso...

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Bibliographic Details
Main Authors: Marta Olszewska, Ewa Wiland, Nataliya Huleyuk, Monika Fraczek, Alina T. Midro, Danuta Zastavna, Maciej Kurpisz
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Medical Genomics
Subjects:
Chromosome topology
Familial translocation
Nuclear architecture
Reciprocal chromosome translocation
Sperm chromosomes
Male infertility
Online Access:http://link.springer.com/article/10.1186/s12920-018-0470-7

Internet

http://link.springer.com/article/10.1186/s12920-018-0470-7

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