High-Fat Diet Promotes Macrophage-Mediated Hepatic Inflammation and Aggravates Diethylnitrosamine-Induced Hepatocarcinogenesis in Mice

High-Fat Diet Promotes Macrophage-Mediated Hepatic Inflammation and Aggravates Diethylnitrosamine-Induced Hepatocarcinogenesis in Mice

It has been reported that diet and nutrition play important roles in the occurrence and development of hepatocellular carcinoma (HCC). In this study, we investigated the potential tumor-promoting mechanisms of a high-fat diet (HFD) in mice with dietondiethylnitrosamine (DEN)-induced hepatocarcinogen...

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Bibliographic Details
Main Authors: Huiying Fu, Biqiang Tang, Jiali Lang, Yueguang Du, Beibei Cao, Lushuai Jin, Mingsun Fang, Zhiming Hu, Changpei Cheng, Xia Liu, Qiyang Shou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Nutrition
Subjects:
liver cancer
tumorigenesis
collagen
inflammatory factors
fatty acid
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2020.585306/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2020.585306/full

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