Sclerostin promotes human dental pulp cells senescence

Background Senescence-related impairment of proliferation and differentiation limits the use of dental pulp cells for tissue regeneration. Deletion of sclerostin improves the dentinogenesis regeneration, while its role in dental pulp senescence is unclear. We investigated the role of sclerostin in s...

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Bibliographic Details
Main Authors: Yanjing Ou, Yi Zhou, Shanshan Liang, Yining Wang
Format: Article
Language:English
Published: PeerJ Inc. 2018-10-01
Series:PeerJ
Subjects:
p21
p16
p53
Online Access:https://peerj.com/articles/5808.pdf