Exome sequencing in large, multiplex bipolar disorder families from Cuba.

Bipolar disorder (BD) is a major psychiatric illness affecting around 1% of the global population. BD is characterized by recurrent manic and depressive episodes, and has an estimated heritability of around 70%. Research has identified the first BD susceptibility genes. However, the underlying pathw...

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Main Authors: Anna Maaser, Andreas J Forstner, Jana Strohmaier, Julian Hecker, Kerstin U Ludwig, Sugirthan Sivalingam, Fabian Streit, Franziska Degenhardt, Stephanie H Witt, Céline S Reinbold, Anna C Koller, Ruth Raff, Stefanie Heilmann-Heimbach, Sascha B Fischer, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Stefan Herms, Per Hoffmann, Holger Thiele, Peter Nürnberg, Heide Löhlein Fier, Guillermo Orozco-Díaz, Deinys Carmenate-Naranjo, Niurka Proenza-Barzaga, Georg W J Auburger, Till F M Andlauer, Sven Cichon, Beatriz Marcheco-Teruel, Ole Mors, Marcella Rietschel, Markus M Nöthen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6209204?pdf=render