Disruption of pathways regulated by Integrator complex in Galloway–Mowat syndrome due to WDR73 mutations

Disruption of pathways regulated by Integrator complex in Galloway–Mowat syndrome due to WDR73 mutations

Abstract Several studies have reported WDR73 mutations to be causative of Galloway–Mowat syndrome, a rare disorder characterised by the association of neurological defects and renal-glomerular disease. In this study, we demonstrate interaction of WDR73 with the INTS9 and INTS11 components of Integra...

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Bibliographic Details
Main Authors: F. C. Tilley, C. Arrondel, C. Chhuon, M. Boisson, N. Cagnard, M. Parisot, G. Menara, N. Lefort, I. C. Guerrera, C. Bole-Feysot, A. Benmerah, C. Antignac, G. Mollet
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84472-7

Internet

https://doi.org/10.1038/s41598-021-84472-7

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