The Arginine/ADMA Ratio Is Related to the Prevention of Atherosclerotic Plaques in Hypercholesterolemic Rabbits When Giving a Combined Therapy with Atorvastatine and Arginine

The Arginine/ADMA Ratio Is Related to the Prevention of Atherosclerotic Plaques in Hypercholesterolemic Rabbits When Giving a Combined Therapy with Atorvastatine and Arginine

Supplementation with arginine in combination with atorvastatin is more efficient in reducing the size of an atherosclerotic plaque than treatment with a statin or arginine alone in homozygous Watanabe heritable hyperlipidemic (WHHL) rabbits. We evaluated the mechanism behind this feature by explorin...

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Bibliographic Details
Main Authors: Saskia J. H. Brinkmann, Elisabeth A. Wörner, Nikki Buijs, Milan Richir, Luc Cynober, Paul A. M. van Leeuwen, Rémy Couderc
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
arginine
ADMA
ratio
statins
nitric oxide
cholesterol
Online Access:http://www.mdpi.com/1422-0067/16/6/12230

Internet

http://www.mdpi.com/1422-0067/16/6/12230

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