Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

Jansson et al. design a high content screening system to target inflammation in human brain cells of the blood–brain barrier (pericytes and endothelial cells) to identify inflammatory modifiers. They identify cardiac glycosides as powerful regulators of neuroinflammatory pathways in brain barrier ti...

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Bibliographic Details
Main Authors: Deidre Jansson, Victor Birger Dieriks, Justin Rustenhoven, Leon C. D. Smyth, Emma Scotter, Miranda Aalderink, Sheryl Feng, Rebecca Johnson, Patrick Schweder, Edward Mee, Peter Heppner, Clinton Turner, Maurice Curtis, Richard Faull, Mike Dragunow
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01787-x

Internet

https://doi.org/10.1038/s42003-021-01787-x

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